Sildenafil in the treatment of erectile dysfunction: an overview of
Sildenafil (Viagra) to the rescue! Sildenafil is a phosphodiesterase-5 inhibitor. It rescues the party by stopping PDE-5 from reducing the amount of cGMP in the penis. Mechanism of Action. Erectile dysfunction: Does not directly cause penile erections but affects the response to sexual stimulation. The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the Mechanism of Action. The molecular structure of sildenafil mimics that of cyclic guanosine monophosphate (cGMP). This similarity protects cGMP from degradation because sildenafil can bind to the catalytic site to act as a competitive inhibitor of cGMP-specific PDE-5, the enzyme that normally catalyzes the breakdown of vasodilatory cGMP. mechanism of action for viagra This review focuses on biochemical and pharmacological features of sildenafil, the active component in Viagra, interaction of sildenafil with phosphodiesterase 5, pharmacokinetic parameters, action in smooth muscle, side effects, safety profile and prospects for other uses. Sildenafil (Viagra) is the most effective oral therapy currently available for erectile dysfunction. Patients should be given clear instructions regarding the use of sildenafil. The most common side effects include flushing, headaches, dyspepsia, and
Mechanism of action. Blood is supplied to the penis by the cavernosal arteries (branches of the penile artery), which drain directly into the cavernous space (Fig. 1). The cavernous
Cialis 5 mg; Cialis 10 mg; Cialis 20 mg; Cialis 2.5 mg; General information about the safe and effective use of Cialis. Medicines are sometimes prescribed for conditions other than those described in patient information leaflets. Do not use Cialis for a condition for which it was not prescribed. Do not give Cialis to other people, even if they Tadalafil under the name of Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. cialis 5mg vs 20mg You should never exceed the maximum dose of Cialis in 24 hours. Cialis dosage 20mg is the Cialis max dose for erectile dysfunction when taken as needed or Cost. Pregnancy. Breastfeeding. Precautions. Overdose. Expiration. Questions for your doctor. About Cialis. Cialis is a brand-name prescription drug. It s approved by the Food and Drug Administration (FDA) to treat the conditions below in adult males. Benign prostatic hyperplasia (BPH).
